About us

The study center STZ eyetrial at the Department for Ophthalmology was founded in 2004 by Professor Barbara Wilhelm. In the anniversary year 2019, Tobias Peters, MD, took over the management.

On average, our team oversees more than 30 projects with a wide variety of focuses, including studies according to AMG, MDR, professional-regulations and IITs. In some studies, we have taken on the role of the CRO as well.


III. European Patient Meeting on Achromatopsia - September 16 th 2023 in Tübinge

We warmly welcome you to this special patient day in Tübingen!
The BMBF project Colour Bridge*, the Achromatopsie Self-Help Association, the BCM Family Foundation and the University Hospital of Tübingen have joined as organisers.

We are at ARVO 2023 - April 23.-27. New Orleans

we look forward to good talks and lectures.

Haag Streit video prize DOG 2022

The DOG awards a video prize, donated by HAAG-STREIT Deutschland GmbH, to the AG DOG Clinical Study Centres in recognition of their outstanding film on clinical trials.


We congratulate Prof. Barbara Wilhelm on EVI Top List of Women in European Vision Research and

Ophthalmology 2021

Trial related publications


Bucher K, Rodríguez-Bocanegra E, Dauletbekov D, Fischer MD (2020).

Immune responses to retinal gene therapy using adeno-associated viral vectors - Implications for treatment success and safety.

Prog Retin Eye Res. 2020 Oct 15:100915.

Deutsche Ophthalmologische Gesellschaft (DOG). Recommendations by the DOG for the planning of clinical trials on behalf of third parties: March 2018.

Ophthalmologe. 2019 Feb;116 (Suppl 1):21-24.

Deuter CME, Engelmann K, Heiligenhaus A, Lanzl I, Mackensen F, Ness T, Pleyer U, Stübiger N, Wilhelm B, Lüdtke H, Zierhut M, Doycheva D,

MYCUV-IIT02 Study Group. Enteric-coated mycophenolate sodium in the treatment of non-infectious intermediate uveitis: results of a prospective, controlled, randomised, open-label, early terminated multicentre trial. Br J

Ophthalmol 2018;102(5):647-653.

Reichel FF, Dauletbekov DL, Klein R, Peters T, Ochakovski GA, Seitz IP, Wilhelm B, Ueffing M, Biel M, Wissinger B, Michalakis S, Bartz-Schmidt KU, Fischer MD; RD-CURE Consortium.

AAV8 Can Induce Innate and Adaptive Immune Response in the Primate Eye.

Mol Ther. 2017 Dec 6; 25(12): 2648-2660.

Kelbsch C, Straßer T, Chen Y, Feigl B, Gamlin P, Kardon R, Peters T, Roecklein K, Steinhauer S, Szabadi E, Zele A, Wilhelm H & Wilhelm, B. (2019).

Standards in Pupillography. Frontiers in Neurology, 10.

Kahle N, Peters T, Braun A, Franklin J, Michalik C, Gekeler F, Wilhelm B, retina.net e.V und die TES-RP-Studiengruppe (2021).

Transkorneale Elektro-stimulation bei Retinitis Pigmentosa - Prüfplan einer multizentrischen, prospektiven, randomisierten, kontrollierten und doppel-blinden Studie im Auftrag des Gemeinsamen Bundesausschusses (G-BA Erprobungsrichtlinie).

DOI 10.1007/s00347-021-01360-1; open access

Fischer MD, Ochakovski GA, Beier B, Seitz IP, Vaheb Y, Kortuem C, Reichel FFL, Kuehlewein L, Kahle NA, Peters T, Girach A, Zrenner E, Ueffing M, MacLaren RE, Bartz-Schmidt KU, Wilhelm B (2019).

Efficacy and Safety of Retinal Gene Therapy Using Adeno-Associated Virus Vector for Patients with Choroideremia: A Randomized Clinical Trial. 

JAMA Ophthalmol. 2019 Aug 29;137(11):1247-54

Jolly JK, Wagner SK, Martus P et al. (2020)

Transcorneal Electrical Stimulation for the Treatment of Retinitis Pigmentosa: A Multicenter Safety Study of the OkuStim(R) System (TESOLA-Study).

Ophthalmic Res 63:234-243

Schönbach EM, Strauss RW, Ibrahim MA, Janes JL, Birch DG, Cideciyan AV, Sunness JS, Muñoz B, Ip MS, Sadda SR, Scholl HPN; ProgStar Study Group.

Faster Sensitivity Loss around Dense Scotomas than for Overall Macular Sensitivity in Stargardt Disease: ProgStar Report No. 14.

Am J Ophthalmol. 2020 Aug;216:219-225.

Fischer, MD, S Michalakis, B Wilhelm, D Zobor, R Muehlfriedel, S Kohl, N Weisschuh, GA Ochakovski, R Klein, C Schoen, V Sothilingam, M Garcia-Garrido, L Kuehlewein, N Kahle, A Werner, D Dauletbekov, F Paquet-Durand, S Tsang, P Martus, T Peters, M Seeliger, KU Bartz-Schmidt, M Ueffing, E Zrenner, M Biel and B Wissinger (2020).

Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia: A Nonrandomized Controlled Trial. 

JAMA Ophthalmol. June 2020 Volume 138, Number 6